KIDNEYS NEED GLUTATHIONE

The kidneys act as the filtration system of the human body and eliminate
wastes from the blood, so it is important that they function properly. However,
decreased kidney function can occur in men and women due to a wide range
of causes. Understanding these causes can help people take preventive
measures to preserve their kidney function.

Diabetes
Statistics published by the National Kidney and Urologic Diseases Information
Clearinghouse show that diabetes accounts for almost 44 percent of new
cases of kidney failure. In diabetes, the body is unable to produce enough
insulin or use insulin properly.
Diabetes can lead to high blood sugar levels,
which can damage the blood vessels and contribute to decreased kidney
function.

Cardiovascular Conditions
While the kidneys are responsible for blood filtration, they also rely on an
adequate supply of blood to function properly. According to physicians from
the Mayo Clinic,
cardiovascular conditions that cause an inadequate amount of blood to reach the kidneys can cause decreased
kidney function.
Very low blood pressure can reduce the amount of blood that reaches your kidneys. Blood flow to the kidneys
can also be limited by congestive heart failure or cardiac events such as heart attack.

High Blood Pressure
High blood pressure (hypertension) is another leading cause of decreased kidney function. When someone has high blood
pressure, the heart has to work harder to pump blood throughout the body. According to NKUDIC, this can damage blood
vessels.
If the kidney blood vessels become damaged, the ability of the kidneys to remove wastes and fluid in the body
decreases.
The remaining fluid can cause blood pressure to increase, resulting in a cycle of kidney damage and hypertension.

Chemical Injury
Because the kidneys filter waste products from the blood, ingesting high amounts of toxins can cause a decrease in kidney
function.
Physicians from the Mayo Clinic list alcohol, solvents, fuels, heavy metals and cocaine as examples of toxins that can
hurt the kidneys.
When someone is exposed to high levels of these toxins, the workload of the kidneys is increased and the
blood vessels may become damaged.

Bladder and Ureter Obstruction
According to physicians from the Mayo Clinic, bladder and ureter obstruction can lead to decreased kidney function. When the
bladder and ureters are obstructed, urine cannot be excreted from the body properly. When urine is retained, it can back up into
the kidneys and cause damage to the blood vessels. The bladder and ureters can become obstructed due to kidney stones,
blood clots, nerve disorders and narrowing of the ureters. In men, prostate enlargement can also cause urinary retention that
leads to decreased kidney function.

Read more: http://www.livestrong.com/article/17637-causes-decreased-kidney-function/#ixzz1nWmy2Qv4

Kidney Failure & Dialysis... a few studies on medline.com in relation to Glutathione and kidney

Andreoli SP. Reactive oxygen molecules, oxidant injury and renal disease. Pediatr. Nephrol. 5: 733-742, 1991 Medline

Breborowicz A, Rodela H. Martis L. Oreopoulos DG.
Intracellular glutathione in human peritoneal mesothelial cell exposed in vitro to dialysis
fluid. Int. J. Artif. Organs 19: 268-275, 1996 Medline

Canestrari F, Galli F, Giorgini A, et al. Erythrocyte redox state in uremic anemia: effects of
hemodialysis and relevance of glutathione
metabolism. Acta. Haematol. 91: 187-193, 1994 Medline

Cavdar C, Cansari T, Semin I, et al. Lipid peroxidation and antioxidant activity in
chronic hemodialysis patients treated with recombinant
human erythropoietin. Scand. J. Urol. Nephrol. 31: 371-375, 1997 Medline

Ceballos-Pict I, Witko-Sarsat V, Merad-Boudia M, et al. Glutathione antioxidant system as a marker of oxidative stress in
chronic renal
failure
. Free Radic. Biol. Med. 21: 845-853, 1996 Medline

Chen CK, Liaw JM, Juang JG, Lin TH. Antioxidant enzymes and trace elements in
hemodialyzed patients. Biol. Trace Elem. Res. 58(1-2):
140-157, 1997 Medline

Costagliola C, Romano L, Scibelli G, et al.
Anemia and chronic renal failure: a therapeutic approach by reduced glutathione parenteral
administration. Nephron 61: 404-408, 1992 Medline

Costagliola C, Romano L, Sorice P, Di Benedetto A.
Anemia and chronic renal failure: the possible role of the oxidative state of glutathione.
Nephron 52: 11-14. 1989 Medline

Cristol JP, Bose JY, Badiou S, et al. Erythropoeitin and
oxidative stress in haemodialysis: beneficial effects of vitamin E supplementation.
Nephrol. Dial. Transplant 12: 2312-2317, 1997 Medline

Diamond GL, Zalups RK. Understanding
renal toxicity of heavy metals. Toxicol. Pathol. 26: 92-103, 1998 Medline

DiMari J, Megyesi J, Udvarhelyi N, et al. N-acetyl cysteine ameliorates
ischemic renal failure. American J. Physiol. 272 (3 pt2): F292-8, 1997
Medline

Durak I, Karabacak HI, Buyukkocak S, et al.
Impaired antioxidant defense system in the kidney tissues from rabbits treated with cyclosporin.
Protective effects of vitamins E and C. Nephron 78:207-211, 1998 Medline

Ferguson CL, Cantilena LR Jr. Mercury clearance from human plasma during in vitro dialysis: screening systems for
chelating agents. J.
Toxicol. Clin. Toxicol. 30: 423-441, 1992 Medline

Lund ME, Banner W Jr. Clarkson TW, Berlin M. Treatment of
acute methylmercury ingestion by hemodialysis with N-acetylcysteine
(Mucomyst) infusion and 2,3-dimercaptopropane sulfonate. J. Toxicol. Clin. Toxicol. 22: 31-49, 1984 Medline

Mimic-Oka J, Simic T, Elkmescic V, Dragicevic P. Erythrocyte
glutathione peroxidase and superoxide dismutase activities in different stages
of chronic renal failure. Clin. Nephrol. 44: 44-48, 1995 Medline

Moberly JB, Logan J, Borum PR, et al. Elevation of whole-blood glutathione in
peritoneal dialysis patients by
L-2-oxothiazolidine-4-carboxylate, a cysteine prodrug (Procysteine). J. American Soc. Nephrol. 9:1093-1099, 1998 Medline

Pasaoglu H, Muhtaroglu S, Gunes M, Utas C. The role of the oxidative state of glutathione and
glutathione-related enzymes in anemia of
hemodialysis patients. Clin. Biochem. 29: 567-572, 1996 Medline

Ross EA, Koo LC, Moberly JB. Low whole blood and erythrocyte levels of glutathione in hemodialysis and
peritoneal dialysis patients.
American L. Kidney Disease 30: 489-494, 1997 Medline

Roxborough HE, Mercer C, McMaster D, et al. Plasma Glutathione peroxidase activity is reduced in
haemodialysis patients. Nephron 81:
278-283, 1999 Medline

Salom MG, Ramirez P, Carbonell LF, et al. Protective effect of N-acetyl-L-cysteine on the
renal failure induced by inferior cava occlusion.
Transplantation 65: 1315-1321, 1998 Medline

Schiavon R, Guidi GC, Biasioli S, et al. Plasma glutathione peroxidase activity as an index of
renal function. Eur. J. Clin. Chem. Clin. Biochem.
32: 759-765, 1994 Medline

Torres VE, Bengal RJ, Litwiller RD, Wilson DM. Aggravation of
polycystic kidney disease in Han:SPRD rats by buthionine sulfoxamine. J.
American Soc. Nephrol. 8: 1283-1291, 1997 Medline

Usberti M, Lima G, Arisi M, et al. Effect of exogenous reduced glutathione on the survival of red blood cells in
hemodialyzed patients. J.
Nephrol. 10:261-265, 1997 Medline

Whitin JC, Tham DM, Bhamre S, et al. Plasma glutathione peroxidase  and its relationship to
renal proximal tubule function. Mol. Genet.
Metab. 65:238-245, 1998 Medline

Yoshimura S, Suemizu H, Nomoto Y, et al. Plasma glutathione peroxidase deficiency caused by
renal dysfunction. Nephron 73: 207-211, 1996
Medline

Zachee P. Ferrant A, Daelmans R, et al. Reduced glutathione for the treatment of anemia during
hemodialysis: a preliminary communcation.
Nephron 71: 343-349, 1995 Medline
                             -  When in adaquate high concentrations,
                   Glutathione is the MASTER ANTIOXIDANT IN THE BODY.    


-   heavy metals, toxins as well as bacteria, fungii, virus are  removed by Glutathione.  

-   Because Kidneys FILTER THE BLOOD they require ADAQUATE HIGH CONCENTRATIONS OF GLUTATHIONE
IN ORDER TO AID THEIR NORMAL FUNCTION.  

THERE IS NO MORE EFFICIENT METHOD OF MAKING SURE YOUR   
         BODY HAS ADAQUATE HIGH CONCENTRATIONS OF                   
                   GLUTATHIONE OTHER THAN CONSUMING                           
                                     "GSH-IMMUNITY"

  PROMOTING NORMAL KIDNEY FUNCTION AND HEALTH
CONTACT

Peggy Maki:
250-422-3163 (MTN) (VOICE)

makipeggy@hotmail.com