LUNG DISEASE //// GLUTATHIONE
ASTHMA
BRONCHITIS
ACUTE / CHRONIC
COPD - CHRONIC OBSTRUCTIVE PULMONARY DISEASE
CYSTIC FIBROSIS
EMPHYSEMA
IDIOPATHIC PULMONARY FIBROSIS
ASTHMA
BRONCHITIS
ACUTE / CHRONIC
COPD - CHRONIC OBSTRUCTIVE PULMONARY DISEASE
CYSTIC FIBROSIS
EMPHYSEMA
IDIOPATHIC PULMONARY FIBROSIS
Understanding how CRUCIAL Glutathione is to the total body
and every cell in the body
allows you to realize just how CRUCIAL GLUTATHIONE IS TO THE LUNGS
WHEN GLUTATHIONE IS ADAQUATE IN THE BODY IT IS CONCENTRATED
IN THE
LUNGS / LIVER / EYES / BRAIN AND KIDNEYS
- Each time we inhale we breath in toxins from our enviornment.
- Each minute of every day our lungs are required to handle huge waste and protect the
body as well as supply the O2 we need.
- Each inhalation allows toxins in our enviornment ( about 12 heavy metals minimum, plus
many other toxins ) to enter our body, each of them are in parts / probably trillion but if you don't have
adaquate Glutathione to remove every one of the toxic heavy metals plus toxins from the body; they build up
and cause problems. That is only considering the toxins, then you have virus, bacteria, fungii etc.
GLUTATHIONE IS A HUGE PART OF THE DETOXING OF THE LUNGS IN EVERY BREATH WE TAKE
- Lung disease has many differant causes; bacteria, virus, pollution / enviornment, heriditary, injury.
- If a person has adaquate / high concentrations of Glutathione in the body, there is enough Glutathione
residing inSIDE every cell of the lungs as well as in the fluid of the lungs to be able to
- remove all toxins / heavy metals
- make sure that circulation is adaquate thruout the lungs
- make sure that no virus or bacteria that threatens our lungs can cause a MAJOR CHRONIC HEALTH problem.
In order to ensure healthy lungs........
- Give the body Cysteine / DAILY
- This enables the body to make its own Glutathione to be efficient
- Replenished Glutathione is able to concentrate in the lungs preventing
disease and aiding the
IMMUNE SYSTEM TO MAINTAIN STRENGTH AND BALANCE.
- GSH-Immunity is a Primary Whey Product that allows the body to attain the Cysteine it requires to replenish
the Glutathione.
The following are some publishings from Medline that give you an idea of the connection of Glutathione to the lungs....................
Balansky RB, D’Agostinin F, Zannacchi P, De Flora S. Protection of N-acetylcysteine of the histopathological and cytogenetical damage produced by
exposure of rats to cigarette smoke. Cancer Lett. 64:123-131, 1992 Medline
Baranova H, Perriot J, Albuisson E, et al. Peculiarities of the GSTM1 o/o genotype in French heavy smokers with various types of chronic bronchitis.
Human Genetics 99: 822-826, 1997 Medline
Behr J, Degenkolb B, Maier K, et al. Increased oxidation of extracellular glutathione by bronchoalveolar inflammatory cells in diffuse fibrosing
alveolitis. Eur. Respir. J. 8: 1286-1292, 1995 Medline
Bernard GR. Potential of N-acetylcysteine as treatment for the adult respiratory distress syndrome. Eur. Respir. J. Suppl. 11:496S-498S, 1990
Medline
Bernard GR. N-acetylcysteine in experimental and clinical acute lung injury. American J. Med. 91: (3c):54S-59S, 1991 Medline
Bernard GR, Wheeler AP, Arons MM, et al. A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The antioxidant in ARDS Study Group.
Chest 112: 164-172, 1997 Medline
Bibi H, Schlesinger M, Tabachnik E, et al. Erythrocyte glutathione peroxidase activity in asthmatic children. Ann. Allergy 61: 339-340, 1988 Medline
Borok Z, Buhl R, Grimes GJ, et al. Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis. Lancet 338: 215-216,
1991 Medline
Brigham KL. Oxidant stress and adult respiratory distress syndrome. Eur. Respir. J. Suppl. 11: 4825-4845, 1990 Medline
Brown RK, Kelly FJ. Evidence for increased oxidative damage in patients with cystic fibrosis. Pediatr. Res. 36: 487-493, 1994 Medline
Buhl R, Meyer A, Vogelmeier C. Oxidant-protease interaction in the lung. Prospects for antioxidant therapy. Chest 110 (6Suppl): 267S-2727S, 1996
Medline
Buhl R, Vogelmeier C. Therapy for lung diseases with anti-oxidants. Pneumologie 48: 50-56, 1994 Medline
Buhl R, Vogelmeier C, Critinden, et al. Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly
administering glutathione aerosol. Proc. Natl. Acad. Sci. USA 87: 4063-4067, 1990 Medline
Bunnel E, Pacht ER. Oxidized glutathione is increased in the alveolar fluid of patients with the adult respiratory distress syndrome. American Rev.
Respir. Dis. 148: 1174-1178, 1993 Medline
Cantin A, Crystal RG. Oxidants, antioxidants and the pathogenesis of emphysema. Eur. J. Dis. Suppl. 139:7-17, 1985 Medline
Cantin A, Hubbard RC, Crystal RG. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis.
American Rev. Respir. Dis. 139: 370-372, 1989 Medline
Cato A, Goldstein I, Millman. A double-blind parallel study of acetylcysteine-isoproterenol and saline-isoproterenol in patients with chronic obstructive
lung disease. J. Int. Med. Res. 5:175-183, 1977 Medline
Conaway CC, Jiao D, Kelloff GJ, et al. Chemopreventive potential of fumaric acid, N-acetylcysteine, N-(4-hydroxyphenyl) retinamide and beta-carotene for
tobacco-nitrosamine-induced lung tumors in A/J mice. Cancer Lett. 124:85-93, 1998 Medline
Cotgreave IA, Moldeus P. Lung protection by thiol-containing antioxidants. Bull. Eur. Physiopathol. Respir. 23: 272-277, 1987 Medline
D’Agostini F, Bagnasco M. Giunciuglio D, et al. Inhibition by oral N-acetylcysteine of doxorubicin-induced clastogenicity and alopedia, and prevention of
primary tumors and lung metastasis in mice. Int. J. Oncol. 13: 217-224, 1998 Medline
Davreux CJ, Soric I, Nathens AB, et al. N- acetyl cysteine attenuates acute lung injury in the rat. Shock 8: 432-438, 1997 Medline
Demling R, Ikegami K, Lalonde C. Increased lipid peroxidation and decreased antioxidant activity correspond with death after smoke exposure in the rat.
J. Burn Care Rehabil. 16(2Pt1): 104-110, 1995 Medline
Demling R, Lalonde C, Picard L. Blanchard J. Changes in lung and systemic oxidant and antioxidant activity after smoke inhalation. Shock 1 :101-107,
1994 Medline
Eiserich JP, Van Der Vliet, et al. Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction. American J. Clin. Nutr.
62(6Suppl): 1490S-1500S, 1995 Medline
Goldstein RH, Fine A. Potential therapeutic initiatives for fibrogenic lung diseases. Chest 108: 848-855, 1995 Medline
Greene LS. Asthma and oxidant stress: nutritional, environmental and genetic risk factors. J. American Coll. Nutr. 14: 317-324, 1995 Medline
Gressier B, Lebegue S, Gosset P, et al. Protective role of glutathione on alpha ! proteinase inhibitor inactivation by the myeloperoxidase system.
Hypothetic study for the therapeutic strategy in the management of smoker’s emphysema. Fundam. Clin. Pharmacol. 8: 518-524, 1994 Medline
Hull J, Vervaart P, Grimwood K, Phelan P. Pulmonary oxidative stress response in young children with cystic fibrosis. Thorax 52: 557-560, 1997 Medline
Hunninghake GW, Kalica AR. Approaches to the treatment of pulmonary fibrosis. American J. Respir. Crit. Care Med. 151(3Pt1): 915-918, 1995 Medline
Ikegami K, Lalonde C, Young YK, et al. Comparison of plasma reduced glutathione and oxidized glutathione with lung and liver tissue oxidant and
antioxidant activity during acute inflammation. Shock 1: 307-312, 1994 Medline
Kadrabova J., Mad’aric A, Kovacikova Z, et al. Selenium status is decreased in patients with intrinsic asthma. Biol. Tr. Elem. Res. 52: 241-248, 1996
Medline
Kelly FJ, Cotgrove M, Mudway IS. Respiratory lining tract fluid antioxidants: the first line of defense against serious gaseous pollutants. Cent. Eur. J.
Public Health 4 Suppl:11-14, 1996 Medline
Lands LC, Grey VL, Grenier. Total plasma antioxidant capacity in cystic fibrosis. Pediatr. Pulmonol. 29:81-87, 2000 Medline
MacNee W. Chronic obstructive pulmonary disease from science to the clinic: the role of glutathione in oxidant-antioxidant balance. Monaldi. Arch.
Chest Dis. 52:479-485, 1997 Medline
Meyer A, Buhl R, Kampf S, Magnussen H. Intravenous N-acetylcysteine and lung glutathione of patients with pulmonary fibrosis and normals.
American J. Respir. Crit. Care Med. 152: 1055-1060, 1995 Medline
Misso NL, Powers KA, Gillon RL, et al. Reduced platelet glutathione peroxidase activity and serum selenium concentration in atopic asthmatic patients.
Clin. Exp. Allergy 26: 838-847, 1996 Medline
Morris PE, Bernard GR. Significance of glutathione in lung disease and implications for therapy. American J. of Med. Sci. 307: 119-127, 1994 Medline
Novak Z, Nemeth I, Gyurkovits K, et al. Examination of the role of oxygen free radicals in bronchial asthma in childhood. Clin. Chim. Acta. 201: 247-
251, 1991 Medline
Parr GD, Huitson A. Oral Fabrol (oral N-acetylcysteine) in chronic bronchitis. Br. J. Dis. Chest 81: 341-348, 1987 Medline
Portal BC, Richard MJ, Faure HS, et al. Altered antioxidant status and increased lipid peroxidation in children with cystic fibrosis. Amer. J. Clin. Nutr. 61:
843-847, 1995 Medline
Powell CV, Nash AA, Powers HJ, Primhak RA. Antioxidant status in asthma. Pediatr. Pulmonol. 18: 34-38, 1994 Medline
Rasmussen JB, Clennow C. Reduction in days of illness after long-term treatment with N-acetylcysteine controlled-release tablets in patients with chronic
bronchitis. Eur. Respirol. J. 4: 351-355, 1988 Medline
Ruse GC, Larsson P, et al. The intrabronchial microbial flora in chronic bronchitis patients: : a target for N-acetylcysteine therapy? Eur. Respir. J. 7:94-
101, 1994 Medline
Rogers DF, Jeffery PK. Inhibition by oral N-acetylcysteine of cigarette smoke-induced “bronchitis” in the rat. Exp. Lung Res. 10: 267-283, 1986
Medline
Suter PM, Domenighetti G, Schaller, et al. N-acetylcysteine enhances recovery from acute lung injury in man. A randomized, double-blind, placebo-
controlled clinical study. Chest 105: 190-194, 1994 Medline
Tanswell AK, Freeman BA. Antioxidant therapy in critical care medicine. New Horiz. 3:330-341, 1995 Medline
Tattersall AB, Bridgman KM, Huitson A. Irish general practice study of acetylcysteine (Fabrol) in chronic bronchitis. J. Int. Med. Res. 12:96-101, 1984
Medline
Teramoto S, Fukuchi Y, Uejima Y, et al. Superoxide anion formation and glutathione metabolism of blood in patients with idiopathic pulmonary fibrosis.
Biochem. Mol. Med. 55: 66-70, 1995 Medline
Van Zandwijk N. N-acetylcysteine (NAC) and glutathione: antioxidant and chemopreventative properties, with special reference to lung cancer. J. Cell.
Biochem. Suppl. 22:24-32, 1995 Medline
Van Zandwijk N. N-acetylcysteine for lung cancer protection. Chest 107: 1437-1441, 1995 Medline
Vina j, Servera E, Aseni M, et al. Exercise causes blood glutathione oxidation in chronic obstructive pulmonary disease: prevention by O2 therapy. J.
Appl. Physiol. 81: 2198-2202, 1996 Medline
Volkl KP, Schneider B. Therapy of respiratory tract diseases with N-acetylcysteine. An open therapeutic observation study of 2, 512 patients. Fortschr.
Med. 110: 346-350, 1992 Medline
White CW, Repine JE. Pulmonary antioxidant defense mechanisms. Exp. Lung Res. 8:81-96, 1985 Medline
Winklhofer-Roob BM. Oxygen free radicals and antioxidants in cystic fibrosis: the concept of an oxidant-antioxidant imbalance. Acta. Paediatr. Suppl.
83: 49
Perhaps this gives you an idea of the research in regards to Glutathione and Lungs.
Allowing the body to replenish Glutathione is a win / win situation for a person with lung problems, a great
deal of success has been proven with high concentrations / adaquate Glutathione in the lungs and lung
disease. Recovery is certainly not out of the question.
Please contact me for more information regarding GSH-Immunity for the best possible Cysteine
/ Glutathione Precursor.
