Diabetes / GSH

Diabetes Types

  • Type 1 diabetes, an Autoimmune disease where the pancreas produces very little insulin or no insulin at all. People who get Type 1 diabetes are usually under the age of 20, usually presenting itself when the person is a child or young adult.
  • Type 2 diabetes is normally found in people who are overweight as they get older. Although it is sometimes called adult onset diabetes, in some countries, such as the United States, more children and young adults are being diagnosed with Type 2 diabetes because they are not getting enough activity.
  • About 90 percent of all cases of diabetes are Type 2 diabetes. The difference between Type 1 and Type 2 diabetes is that with Type 2 diabetes the pancreas does not produce enough insulin or the body does not properly use it.
  • Gestational diabetes, which is a condition that women can get when they are in the second trimester of pregnancy. About 4 percent of all pregnant women will develop gestational diabetes. Unlike Type 1 and Type 2 diabetes, gestational diabetes will disappear after the baby is born.


If a woman has an occurance of gestational diabetes during pregnancy, she is more likely to have it again in the next pregnancy and puts the woman at a higher risk of developing Type 2 diabetes later in life. The older a woman is when she is pregnant, the higher the risk of developing gestational diabetes during pregnancy.

SYMPTOMS OF DIABETES IN ADULTS:

There are many signs and symptoms that can indicate diabetes. Signs and symptoms can include the following: Unusual thirst, Frequent urination, Weight change (gain or loss), Extreme fatigue or lack of energy, Blurred vision, Frequent or recurring infections, Cuts and bruises that are slow to heal, Tingling or numbness in the hands or feet, Trouble getting or maintaining an erection. If you have any of these symptoms; it is important to contact your healthcare provider right away. Even if you don’t have symptoms, if you are 40 or older, you should still get checked. It is important to recognize however, that many people who have type 2 diabetes may display no symptoms.

SYMPTOMS OF DIABETES IN CHILDREN:

Diabetes affects children of all ages. Most children who develop diabetes do not have a family history of diabetes. Symptoms of diabetes in your child could include: Drinking and going to the bathroom more frequently than usual, Starting to wet the bed again, Lack of energy. If you think your child might have diabetes, see a doctor today.

EFFECTS OF DIABETES ON BODY:

Many of the effects of diabetes stem from the same guilty parties; namely high blood pressure, high cholesterol levels and a lack of blood glucose control.

  • Diabetes affects our blood vessels and nerves and therefore can affect any part of the body.
  • The uncontrolled effects of diabetes on the body can be noticed by the classic symptoms of diabetes, namely:


    Increased thirst
    Frequent need to urinate
    Fatigue
    Blurred vision
    Tingling or pain in the hands, feet and/or legs

  • Diabetes and coronary heart disease are closely related: Diabetes contributes to high blood pressure and is linked with high cholesterol, which significantly increases the risk of heart attacks and cardiovascular disease including stroke.

Diabetes / Strokes:

Similar to how diabetes affects the heart, high blood pressure and cholesterol raises the risk of strokes.

Diabetes / Eyes:

A relatively common complication of diabetes is diabetic retinopathy.

Retinopathy is caused by blood vessels in the back of the eye (the retina) swelling and leaking. High blood pressure is also a contributing factor for diabetic retinopathy.

Diabetes / Kidneys:

Kidney disease amongst diabetics is commonly called diabetic nephropathy.

Statistically, around 40% of people with diabetes develop nephropathy but it is possible to prevent or delay through control of both blood glucose and blood pressure levels.

Diabetes affects the arteries of the body and as the kidneys filter blood from many arteries, kidney problems are a particular risk for people with diabetes Kidney disease amongst diabetics is commonly called diabetic nephropathy.

Statistically, around 40% of people with diabetes develop nephropathy but it is possible to prevent or delay through the control of both blood glucose and blood pressure levels.

Diabetes affects the arteries of the body and as the kidneys filter blood from many arteries, kidney problems are a particular risk for people with diabetes.

Diabetes / Nerves:

  • The effects of diabetes on the nerves can be serious as the nerves are involved in so many of our bodily functions, from movement and digestion through to sex and reproduction.
  • The presence of nerve damage (neuropathy) is commonly noticed by:


    Numbness or tingling in the hands or feet
    Lack of arousal in the penis or clitoris
    Excessive sweating

  • Diabetes and coronary heart disease are closely related: Diabetes contributes to high blood pressure and is linked with high cholesterol, which significantly increases the risk of heart attacks and cardiovascular disease including stroke.

Diabetes / Digestion:

Diabetes can affect digestion in a number of ways. If diabetes has caused nerve damage, this can lead to nausea, constipation or diarrhea.

An alternative cause of disturbed digestion can be the result of diabetes medication

JOBS OF GLUTATHIONE IN RELATION TO DIABETES

A: Antioxidant ( Master Antioxidant )
I: Immune System BALANCE AND STRENGTHENING
D: Detoxification

A: Master Antioxidant:

Any imbalance between the free radicals and antioxidants leads to produce a condition known as “oxidative stress” that results in the development of pathological condition among which one is diabetes.

Most of the studies reveal the inference of oxidative stress in diabetes pathogenesis by the alteration in enzymatic systems: impaired Glutathione metabolism. Oxidative stress induced complications of diabetes may include stroke, neuropathy, retinopathy and nephropathy.

GSH is the Master Antioxidant, so long as you have adequate GSH intracellular, the cells are able to remove free radicals, thus stabilizing the diabetic which aids in preventing Oxidative Stress complications.

I: Immune System:

The immune system plays an important role in the body by keeping us free from infection.
As with other organ systems, problems with the immune system can occur, leading to the development of long term conditions, including type 1 and type 2 diabetes.

Immune system and type 2 diabetes:

Researchers have linked insulin resistance to high levels of cytokines, which are released in response to inflammation in the body.

The immune's system's response to inflammation leads to fat cells being unable to respond well to insulin and sees the fat cells releasing fatty acids into the blood, leading to higher than normal levels of cholesterol.

IF a person has adequate GSH, the Immune system is Balanced and Strong. infection in the form of virus or bacteria in a diabetic body can be very dangerous. If a person has diabetes; allowing your cells to replenish their own GSH will aid against infections because of the Stronger and Balanced Immune System, also, if a person gets an infection GSH will lessen the intensity and duration of the infection.

Immune System and type 1 diabetes:

In Type 1 diabetes urinary, skin, ear, nose and throat infections are common.

Sensory neuropathy, atherosclerotic vascular disease, and hyperglycemia all predispose patients with diabetes to skin and soft tissue infections. These can affect any skin surface but most commonly involve the feet.

Again, a person with diabetes is deficit in GSH, if they replenish their GSH, the Immune system becomes Strong and Balanced, in this case if a bacterium or virus attack the body the person is better able to fight the infection, shorter duration and less intense.

D: DETOXIFICATION:

Research 2014

Persistent organic pollutants (POPs) resist biodegradation and are ubiquitous in the environment and food chain. New data reveal that levels of POPs in human serum and adipose tissue are significantly correlated with glucose levels determined during an oral glucose tolerance test. The results suggest that environmental levels of POPs may be diabetogenic.

Toxins can be a cause of and also contribute to the progression of diabetes. If a person has a toxic overload it is necessary to replenish GSH daily, there is NO more efficient nor effective chelator of toxins in our body, both intra and extra cellular than GSH is. It is a Sulphur based molecule that recognizes the antigens, attaches itself to the antigen, then removes it through the kidneys or digestive system and liver to colon.

Diabetes / Glutathione research

2015: Studies reveal the inference of oxidative stress in diabetes pathogenesis by the alteration in enzymatic systems, lipid peroxidation, impaired Glutathione metabolism and decreased Vitamin C levels.

Lipids, proteins, DNA damage, Glutathione, catalane and superoxide dismutase are various biomarkers of oxidative stress in diabetes mellitus.

Oxidative stress induced complications of diabetes may include stroke, neuropathy, retinopathy and nephropathy.

2011: CONCLUSIONS Patients with uncontrolled type 2 diabetes have severely deficient synthesis of glutathione attributed to limited precursor availability. Dietary supplementation with GSH precursor amino acids can restore GSH synthesis and lower oxidative stress and oxidant damage in the face of persistent hyperglycemia.

  • According to Wiley InterScience, "Increasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus. Free radicals are formed disproportionately in diabetics."
  • "Abnormally high levels of free radicals and the simultaneous decline of antioxidant defense mechanisms can lead to the development of insulin resistance. These consequences of oxidative stress can promote the development of complications of diabetes mellitus." Diabetics also have low levels of intracellular glutathione (GSH).
  • According to Science Direct, "Analyses of whole blood GSH showed that GSH was significantly lower in diabetic cases compared to the other groups...."
  • "The high levels of oxidative stress and the low glutathione (GSH) levels further complicates the diabetic state which leads to even higher levels of oxidative stress and even lower levels of GSH.
  • "Furthermore, inflammation leads to and contributes to insulin resistance. Glutathione, on top of being the most potent antioxidant, is also a powerful ant-inflammatory."
  • J. Investig Medical stated, "...there is evidence for increased oxidative stress in diabetics. With regard to diabetes, antioxidants supplementation have been shown to be beneficial. Thus, it appears that, in diabetes, antioxidant therapy could alleviate the increased attendant oxidative stress and emerge as an additional therapeutic modality."
  • ScienceDaily concludes, "Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation leads to insulin resistance and Type 2 diabetes."

GLUTATHIONE REPLENISHING IS CRUCIAL FOR THE DIABETIC FOR AID AGAINST PROGRESSION OF THE DISEASE AND ALSO EFFECTS OF DIABETES ON THE BODY. REPLENISHING IS EASY AND EXTREMELY EFFECTIVE IF DONE CORRECTLY. Please contact me for more information on how to replenish YOUR GSH.